S7® Nitric Oxide Blend: Caffeine-Free Performance Booster

Published: February 01, 2026
5 Min Read
S7® Nitric Oxide Blend: Caffeine-Free Performance Booster

Overview

S7® is a patented blend of seven plant extracts that functions as a natural nitric oxide (NO) booster. Maeva’s Energy Booster includes S7® to enhance circulation and stamina without stimulants. The S7® blend (green coffee bean, green tea, turmeric, tart cherry, blueberry, broccoli, and kale) works by stimulating the body’s own NO production pathways rather than providing exogenous nitrates. NO is a vasodilator, it relaxes blood vessels, improving blood flow to muscles and the brain, which can translate to better exercise performance, reduced fatigue, and sharper focus. Even on low-calorie days or when energy is low, S7® helps maintain “pump” and endurance by ensuring muscles are well-oxygenated and nourished.

Evidence: 230% Nitric Oxide Increase

The efficacy of S7® was demonstrated in a peer-reviewed human study published in Free Radical Research. In that pilot trial, a single 50 mg dose of S7® led to a remarkable 230% increase in blood nitric oxide levels above baseline in healthy adults. This is a 3.3-fold boost in NO, achieved without any dietary nitrates like beetroot. Such a significant elevation indicates substantially improved vasodilation.

Participants taking S7® would likely experience better blood circulation; indeed, users often report enhanced muscle “pump” during workouts and improved exercise tolerance when using S7®. The same study noted that S7® supplementation also reduced oxidative stress, specifically, it inhibited mitochondrial and cellular reactive oxygen species generation by up to ~17% . This antioxidant effect may further support endurance by mitigating exercise-induced free radical buildup.

Sports Performance Benefits

While S7® is relatively new, its impact on performance is promising. By raising NO, it can mimic the effects of more oxygen reaching muscles. Greater NO means more nutrient and oxygen delivery during exercise and more efficient removal of metabolic wastes (like lactic acid). Athletes often feel this as the ability to push out a few extra reps or maintain higher intensity longer. Although the gold-standard for NO boosters has been beetroot (nitrate), S7®’s appeal is that it’s stimulant-free and nitrate-free, relying instead on polyphenol-rich botanicals to signal NO pathways.

According to FutureCeuticals (the developer), S7®’s clinical trial participants had notable improvements in exercise readiness and blood flow markers. Additionally, because S7® lacks caffeine, it provides a “steady” energy without jitters or crashes, aligning with Maeva’s goal for a smooth, jitter-free energy support.

Mechanism

The exact mechanism by which S7® increases NO is through upregulation of endothelial nitric oxide synthase (eNOS) via the polyphenols’ antioxidant activity. Ingredients like turmeric and green tea are known to enhance endothelial function. S7®’s blend may reduce NO-quenching free radicals (hence more NO bioavailability) and directly stimulate NO release from the endothelium. The dose used in Maeva’s Energy Booster is 50 mg of S7® (per scoop) – which is the same effective dose shown to boost NO in the study. This means each serving can acutely raise your NO levels during a workout or on a long workday when you need better circulation to stay energized.

Real-World Effects

What can users expect? With improved NO, you might notice better exercise performance, e.g. muscles feel less fatigued and recover faster between sets, or an overall improvement in endurance for cardio. Some users describe more visible vascularity or “pump” due to vasodilation, which is a positive sign of increased blood flow. Importantly, S7® achieves this without caffeine or synthetics, so it’s suitable for those who are stimulant-sensitive or taking GLP-1 medications (who should avoid extra heart rate spikes).

Maeva’s Energy Booster leverages S7® to provide “steady energy and focus” by ensuring your brain and body are well-perfused with blood and nutrients. This can translate to clearer thinking and less mental fog as well, since NO also improves cerebral blood flow. One study on a similar polyphenol blend showed enhanced cognitive function during tasks, likely due to better brain oxygenation (though S7®v-specific cognitive data is still emerging).

Additionally, improved circulation can support muscle recovery, as more blood flow helps clear metabolic waste post-exercise. Users might find they have less muscle soreness or quicker recovery when using S7® regularly, especially alongside Maeva’s high-quality protein and creatine. The antioxidant aspect of S7® (noted by reduced ROS) further aids recovery and overall health.

Summary

In summary, S7® is a cutting-edge, plant-based NO booster clinically shown to amplify nitric oxide by 230%. By including it, Maeva’s Energy Booster naturally supports better circulation, endurance, and focus during workouts or busy days, without caffeine crashes. It’s a prime example of Maeva’s science-first approach: leveraging a small but mighty dose of botanical extracts to yield significant physiological benefits. With S7® on board, users get a daily circulation boost that complements exercise and helps combat the lower energy levels sometimes experienced on GLP-1 therapy.