Replenwell® Collagen: Peptides for Skin Youthfulness
Overview
Collagen peptides are the building blocks of our skin’s structural matrix. Maeva’s Beauty Booster features Replenwell® Collagen, a trademarked bioactive collagen known for its clinically proven benefits to skin elasticity, hydration, and overall “beauty from within”. Replenwell® is a hydrolyzed collagen (from bovine source) optimized to be rich in specific dipeptides (like proline-hydroxyproline, “PO”, and hydroxyproline-glycine, “OG”) that have enhanced absorption and activity in skin tissue. These small peptide units circulate in the bloodstream for hours and get incorporated into the dermis, where they stimulate fibroblast cells to produce collagen and hyaluronic acid. The net result is improved skin moisture, firmness, and reduced wrinkles, outcomes validated by multiple human trials.
Clinically Studied Skin Benefits
Replenwell® Collagen’s efficacy is backed by at least five randomized, placebo-controlled trials on skin aging.
For instance, in one 8-week study, a collagen supplement high in PO and OG peptides led to significant improvements in skin hydration, elasticity, wrinkle depth, and roughness compared to placebo. Women taking the bioactive collagen showed measurably moister, more elastic skin, and had visibly reduced fine lines after 4–8 weeks.
Another trial found that Replenwell® collagen at 5 g/day increased skin moisture and suppleness while decreasing dryness and scaling in just 6 weeks (data from internal clinical dossiers). A 2021 meta-analysis of oral collagen supplements concluded that they consistently improve skin hydration and elasticity and reduce wrinkles relative to placebo – exactly the benefits Maeva’s Beauty Booster is designed to deliver.

Replenwell®’s peptides work by triggering the skin’s repair mechanisms. When collagen peptides rich in PO/OG are ingested, they act as “signal peptides” in the dermis – fibroblasts detect these fragments and ramp up production of new collagen, elastin, and hyaluronic acid . At the same time, collagen breakdown slows. This dual action helps restore skin structure from within.
In the Inoue et al. (2016) study, the high-dipeptide collagen group saw greater gains in facial skin elasticity and moisture and significantly fewer wrinkles than both placebo and a standard collagen group. Notably, objective measurements (like skin hydration via corneometry and 3D wrinkle imaging) confirmed these improvements. By 8 weeks, women on Replenwell®-type collagen had smoother skin surface and reduced wrinkle volume on the face. These results are echoed across trials – a recent summary of 7 RCTs found statistically significant improvements in skin hydration and elasticity, along with a measurable decrease in wrinkle depth, among those taking daily oral collagen.
Why Replenwell®?
Not all collagens are equal. Replenwell® is a patented, enzymatically hydrolyzed collagen engineered to yield high levels of the bioactive PO and OG dipeptides. Studies show these dipeptides are uniquely stable in the bloodstream and preferentially accumulate in skin tissue. In fact, PO has been detected inside skin cells and shown to directly stimulate hyaluronic acid synthesis in vitro.
This likely underlies the significant increase in skin moisture observed in volunteers taking Replenwell® collagen. Furthermore, Replenwell® won industry awards (Ingredient of the Year for Beauty, 2021) for its robust science. Maeva includes 2.5 g of Replenwell® peptides per scoop – an effective dose given that as little as 2.5–5 g collagen daily can yield skin benefits in trials.
Synergy in the Beauty Booster
Replenwell® Collagen in Maeva’s formula works in concert with other skin nutrients. It’s paired with hyaluronic acid to further boost skin hydration and plumpness, and with Ohtaka® ceramides to strengthen the skin barrier and lock in moisture. Additionally, vitamin C is included to support collagen synthesis and protect against oxidative stress to the skin. By combining collagen peptides with these cofactors, Maeva maximizes the pro-collagen environment in the body.
The result is a comprehensive “inside-out” approach to beauty: collagen provides the dermal scaffolding, hyaluronic acid draws and retains water, ceramides prevent water loss, and vitamin C ensures proper collagen cross-linking. Users can expect improvements in skin elasticity (firmer, bouncier skin) and skin hydration – for instance, fewer dry patches and a dewier complexion – within 1–2 months of consistent use. Over longer periods, fine lines may soften as the collagen network rebuilds.
Summary
In summary, Replenwell® Collagen is a science-driven ingredient that enhances skin elasticity and moisture while reducing visible signs of aging like wrinkles. By including this clinically tested collagen in the Beauty Booster, Maeva provides tangible dermatological benefits backed by human studies – all with an unflavored powder that’s easy to add to your daily shake.